7/9/2023 0 Comments Cytiva capto q![]() The modified agarose matrix provides greater particle rigidity without compromising pore size, which allows more flexibility in process-scale applications. Capto media are intended for general use in large-scale bioprocess operations. CaptoQ has a strong quaternary ammonium (Q) anion exchanger coupled to a chemically modified, high-flow agarose matrix. Capto Q manufactured by Cytiva is a strong anion exchanger for high-productivity and cost-effective capture and intermediate protein purification when high. Capto media are based on a highly rigid agarose base matrix that offers outstanding pressure/flow properties, optimized pore structure, and very high chemical stability to support CIP procedures. ![]() High throughput in downstream purification requires separation media that combine mechanical strength of the matrix with a pore structure that allows fast mass transfer and high capacity for target molecules. Cytiva HiTrap Capto Q ImpRes, 5 x 1 ml HiTrap Capto Q ImpRes is a strong anion exchanger prepacked with BioProcess Capto ImpRes media for screening and. Cost-effective processing with smaller unit operations By combining high-flow characteristics of Capto with a small particle size, Capto Q ImpRes delivers high resolution and excellent pressure-flow properties. The use of Capto Core 700 and Capto Q ImpRes in the purification of human papilloma virus like particles.Reducing process time with high volume throughput.Raising productivity with high dynamic binding capacity at high flow.As BioProcess™ media, the Capto range meets the demands of large-scale biopharmaceutical manufacturers by: They combine high capacity with high flow velocity and low backpressure to reduce process cycle times and increase productivity. HiScreen Capto Q is a column packed with a strong anion exchange modern resin, combining speed and capacity. Preprogrammed, verified packing methods that include Capto, MabSelect media Reproducible, predictable and scalable results. The load of protein was at 60 mg mAb/mL resin with the mAb dissolved in respective buffer, that is, with a pH range of 4 to 6.5 and citrate buffer concentrations of 25 to 350 mM. Datasheet: Capto™ S, Capto Q, And Capto DEAEĬapto S, Capto Q and Capto DEAE are, respectively, strong cation, strong anion and weak anion exchange media for packed bed chromatography that increase speed and throughput in capture and intermediate purification. We screened three resins: Capto Butyl, Capto Phenyl ImpRes, and Capto Phenyl (High Sub) with 6 µL of a single resin filled in a 96-well PreDictor plate.
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